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Next-generation Alzheimer's drug shows lower brain bleed risk in trials

A next-generation Alzheimer's drug called trontinemab has shown a much lower risk of serious brain bleeds compared to existing antibody treatments, according to research presented at the Alzheimer's Association International Conference in London. The Roche-developed drug also cleared amyloid plaques from the brain more quickly, with effects lasting at least a year. Brain bleeds, known as ARIA, have been a major safety concern with current amyloid-clearing therapies like Leqembi and Kisunla.

FDA panel eases restrictions on peptides as lab-grown mini brains predict Alzheimer's drug response

An FDA advisory panel voted to ease restrictions on some peptides over agency scientists' objections. Separately, researchers at Sciencedaily reported that lab-grown mini brains grown from patients' cells can predict which Alzheimer's treatments will work. The organoids revealed striking differences in how Alzheimer's-related tissue responds to an antidepressant, opening the door to more personalized treatments.

Colorectal cancer now leading cause of cancer death in adults under 50

The American Cancer Society's 2026 report reveals colorectal cancer is now the leading cause of cancer death in Americans under 50, with 158,850 new cases and 55,230 deaths expected this year. Incidence in adults 20-49 is rising 3% annually, driven by distal colon and rectal tumors.

Colorectal cancer becomes top cancer killer in adults under 50, researchers warn

Colorectal cancer has become the leading cause of cancer death among people under 50, with cases in younger adults continuing to rise, according to new research published this week. Scientists are urgently investigating why rates are climbing in younger populations, with diet, gut microbiome changes, and environmental factors all under scrutiny. Warning signs include persistent bowel changes, rectal bleeding, dark or narrow stools, and unexplained weight loss. The American Cancer Society now recommends screening begin at age 45 for average-risk adults, but many younger patients are diagnosed at later stages when treatment is less effective.

Colorectal cancer becomes top cancer killer in adults under 50 as cases rise

Colorectal cancer is now the leading cause of cancer death among people under 50, and cases in younger adults continue to rise, according to new research. Warning signs include persistent bowel changes, recurring rectal bleeding, dark or narrow stools, and unexplained weight loss. Meanwhile, scientists discovered a protein called SORLA that protects the brain from Alzheimer's damage, and an AI-powered blood test can predict heart disease 15 years early.

Colorectal cancer is now the top cancer killer of Americans under 50

Colorectal cancer has become the leading cause of cancer death in adults under 50 in the United States, according to a JAMA study and ACS annual report. Death rates from colorectal cancer in this age group have been rising by 1.1% annually since 2005, while deaths from other major cancers have declined. In a separate development, researchers at Umeå University developed a fully human antibody that halted aggressive prostate cancer growth and spread in preclinical models.

Common antidepressant eases long COVID fatigue in clinical trial

A low-cost antidepressant called fluvoxamine significantly reduced fatigue and improved quality of life in a randomized clinical trial of 399 adults with long COVID. The study, published in a peer-reviewed journal, offers hope for millions suffering from persistent fatigue after coronavirus infection. Researchers found that participants taking the drug reported measurable improvements compared to the placebo group, with effects sustained over the trial period.